- Medication Administration
- Drug Effects
- Desired effect: action for which drug is prescribed
- Adverse effect: harmful unintended reaction
- Toxic effect: serious adverse effect that occurs when plasma concentration of drug reaches dangerous, life threatening level.
- Side effect: response that is unrelated to desired action of drug
- Cumulative action: when repeated doses of the drug accumulate in body and exert greater biologic effect that the initial dose
- Drug dependence: physical or psychological reliance on chemical agent resulting from continued use, abuse, or addiction
- Idiosyncratic response: individual’s unique, unpredictable response
- Paradoxical reaction: response that contrast sharply with usual, expected response
- Tolerance: ability to endure ordinarily injurious amounts of drug or decreasing effect obtained from established dose; requires increasing dose to possibly toxic level to maintain same effect
- Hypersensitivity: excessive allergic reaction to exogenous agent
- Anaphylaxis: life threatening episode of bronchial constriction and edema that obstructs airway and causes generalized vasodilation, which depletes circulating blood volume; occurs when an allergen is administered to an individual who has antibodies produced by prior use of the drug
- Uticaria: generalized pruritic skin eruptions or giant hives
- Angioedema: fluid accumulation in periorbital, oral and respiratory tissues
- Delayed reaction allergies: rash and fever occurring during drug therapy
- Drugs and food my interact and alter therapeutic effect adversely
- Antagonist/inhibiting effect: one drug diminishing the effect of another
- Synergistic/potentiating effort: effect of two drugs is greater than either drug alone; often dose must be reduced
